Therapeutical approach and surgery
The goal of our therapeutic approaches is to provide patients with treatment that is:
- Long-lasting (only one life-long intervention)
- Quick and simple to administer
The initial approach, developed by the TargetAMD consortium, comprised the harvest of an iris biopsy, immediate, non-viral genetic modification of the cells by integration of one gene of interest and subretinal transplantation of the autologous cell product. Since then, the approach has been broadened to treat both forms of AMD, early and late stages of the disease using more than one therapeutic gene and stem cell-technology.